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Article

Short communication: HIV type 1 phenotype, tropism, and sequence patterns: association and preference.

AIDS research and human retroviruses - 1 Mar 2005

Dong Xiao-Nan, Chen Xi, Chen Yu, Ablimit Ablikim, Ye Zi, Wu Yi, Chen Ying-Hua

Abstract excerpt

In this study, the relationship between biological phenotypes, coreceptor usages, and sequence patterns of V1V2 or V3 regions on HIV-1 envelope gp 120 was carefully analyzed based on the existing isolates in the Los Alamos National Laboratory sequence database. Obviously, SI/NSI phenotypes were closely linked to the capability of HIV-1 to use coreceptor CXCR4, but not CCR5. Moreover, compared to NSI or R5...

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Topics

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Share to CXCR4 gene
Share to Glycosylation
Share to HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Envelope Protein gp120

Share to HIV Envelope Protein gp160

Share to Phenotype

Share to Receptors, CCR5

Share to Tropism

Source

Identifiers

PMID: 15795530
DOI: 10.1089/aid.2005.21.234

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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