Article
Coreceptor usage and biological phenotypes of HIV-1 isolates.
Clinical chemistry and laboratory medicine - 1 Sept 2002
Cilliers Tonie, Morris Lynn
Abstract excerpt
The discovery of chemokine receptors as HIV-1 entry molecules or "coreceptors" has lead to a greater understanding of how HIV-1 infects human cells. This has provided insight into the biological properties of HIV-1 isolates and unravelled the meaning of the syncytium-inducing and non-syncytium-inducing phenotypes. Understanding how HIV-1 exploits these coreceptors has given way to novel approaches to controlling...
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