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Article

A reliable phenotype predictor for human immunodeficiency virus type 1 subtype C based on envelope V3 sequences.

Journal of virology - 1 May 2006

Jensen Mark A, Coetzer Mia, van 't Wout Angélique B, Morris Lynn, Mullins James I

Abstract excerpt

In human immunodeficiency virus type 1 (HIV-1) subtype B infections, the emergence of viruses able to use CXCR4 as a coreceptor is well documented and associated with accelerated CD4 decline and disease progression. However, in HIV-1 subtype C infections, responsible for more than 50% of global infections, CXCR4 usage is less common, even in individuals with advanced disease. A reliable phenotype prediction...

Topics

HIV Envelope Protein gp120
HIV-1
Humans
Peptide Fragments
Phenotype
Predictive Value of Tests
Reproducibility of Results
Sequence Analysis, DNA

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 16641263
DOI: 10.1128/JVI.80.10.4698-4704.2006
PMCID: PMC1472078

Genes

CXCR4
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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