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Clinical significance of HIV-1 coreceptor usage

27 Jan 2011

Abstract excerpt

The identification of phenotypically distinct HIV-1 variants with different prevalence during the progression of the disease has been one of the earliest discoveries in HIV-1 biology, but its relevance to AIDS pathogenesis remains only partially understood. The physiological basis for the phenotypic variability of HIV-1 was elucidated with the discovery of distinct coreceptors employed by the virus to infect...

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PMID: 21284904
DOI: 10.1186/1479-5876-9-s1-s5

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