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Article

A hypomorphic allele of the first N-glycosylation gene, ALG7, causes mitochondrial defects in yeast.

Biochimica et biophysica acta - 25 May 2005

Mendelsohn Richard D, Helmerhorst Eva J, Cipollo John F, Kukuruzinska Maria A

Abstract excerpt

The modification of proteins at asparagine residues with oligosaccharides (N-glycans) plays critical roles in diverse cell functions. N-glycans originate from a common lipid-linked oligosaccharide (LLO) precursor whose synthesis is initiated by the Dol-P-dependent GlcNAc-1-P transferase (GPT) encoded by an essential ALG7 gene. To identify cellular processes affected by ALG7 and N-glycosylation, we replaced the...

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Identifiers

PMID: 15794922
DOI: 10.1016/j.bbagen.2005.01.017

Genes

GPT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A hypomorphic allele of the first N-glycosylation gene, ALG7, causes mitochondrial defects in yeast.PMID 15794922Read ↗

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