Article
Genetic distinctions between autoimmune hepatitis in Italy and North America.
World journal of gastroenterology - 28 Mar 2005
Muratori Paolo, Czaja Albert-J, Muratori Luigi, Pappas Georgios, Maccariello Silvana, Cassani Fabio, Granito Alessandro, Ferrari Rodolfo, Mantovani Vilma, Lenzi Marco, Bianchi Francesco-B
Abstract excerpt
AIM: Our goals were to analyze the known genetic predispositions for autoimmune hepatitis (AIH) in AIH Italian population and to compare them with North American counterparts. METHODS: Human leukocyte antigens (HLA) B8, C7, DR3, DR4, DR7, DR11, DR13, DQ2 and the B8-DR3-DQ2 phenotype were determined by microlymphocytotoxicity and polymerase chain reaction in 74 Italian patients (57 with type 1 and 17 with type 2...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Child
- Female
- Genetic Predisposition to Disease
- HLA Antigens
- Hepatitis, Autoimmune
- Humans
- Italy
- Male
- Middle Aged
- North America