Article
Genetic heterogeneity in susceptibility to autoimmune hepatitis types 1 and 2.
The American journal of gastroenterology - 1 Jul 1999
Bittencourt P L, Goldberg A C, Cançado E L, Porta G, Carrilho F J, Farias A Q, Palacios S A, Chiarella J M, Abrantes-Lemos C P, Baggio V L, Laudanna A A, Kalil J
Abstract excerpt
OBJECTIVE: Susceptibility to autoimmune hepatitis (AIH) type 1 has been associated with DRB1*03, DRB1*04, and DRB3 alleles in European and North-American whites, with DRB1*04 in Japan, and with DRB1*04 and DRB1*13 in Latin America. Very few studies have been performed on AIH type 2. The aim of the present study was to evaluate the association of AIH types 1 and 2 with HLA-DR and DQ loci. METHODS: We performed...
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