Article
Phenotypic tolerance: antibiotic enrichment of noninherited resistance in bacterial populations.
Antimicrobial agents and chemotherapy - 1 Apr 2005
Wiuff C, Zappala R M, Regoes R R, Garner K N, Baquero F, Levin B R
Abstract excerpt
When growing bacteria are exposed to bactericidal concentrations of antibiotics, the sensitivity of the bacteria to the antibiotic commonly decreases with time, and substantial fractions of the bacteria survive. Using Escherichia coli CAB1 and antibiotics of five different classes (ampicillin, ciprofloxacin, rifampin, streptomycin, and tetracycline), we examine the details of this phenomenon and, with the aid of...
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