Article
Roles for 147 embryonic lethal genes on C.elegans chromosome I identified by RNA interference and video microscopy.
The EMBO journal - 1 Aug 2001
Zipperlen P, Fraser A G, Kamath R S, Martinez-Campos M, Ahringer J
Abstract excerpt
Early embryonic development involves complex events such as the regulation of cell division and the establishment of embryonic polarity. To identify genes involved in these events, we collected four-dimensional time-lapse video recordings of the first three cell divisions and analysed terminal phenotypes after RNA interference of 147 embryonic lethal genes previously identified in a systematic screen of...
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