Article
Cellular phenotyping by RNAi.
Briefings in functional genomics & proteomics - 1 Mar 2006
Fuchs Florian, Boutros Michael
Abstract excerpt
A systematic characterization of genes with unknown function is a key challenge after the sequencing of the human genome and the genomes of many model organisms. High-throughput RNA-interference (RNAi) screenings have become a widely used approach in invertebrate model organisms and also promise to revolutionize cell biology in mammals. Genome-wide RNAi screens in Caenorhabditis elegans and Drosophila, and in a...
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