Article
Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis.
Nature - 11 Aug 2005
Gunsalus Kristin C, Ge Hui, Schetter Aaron J, Goldberg Debra S, Han Jing-Dong J, Hao Tong, Berriz Gabriel F, Bertin Nicolas, Huang Jerry, Chuang Ling-Shiang, Li Ning, Mani Ramamurthy, Hyman Anthony A, Sönnichsen Birte, Echeverri Christophe J, Roth Frederick P, Vidal Marc, Piano Fabio
Abstract excerpt
Although numerous fundamental aspects of development have been uncovered through the study of individual genes and proteins, system-level models are still missing for most developmental processes. The first two cell divisions of Caenorhabditis elegans embryogenesis constitute an ideal test bed for a system-level approach. Early embryogenesis, including processes such as cell division and establishment of cellular...
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