Article
Differential Akt activation in the photoreceptors of normal and rd1 mice.
Cell and tissue research - 1 May 2005
Johnson Leif E, van Veen Theo, Ekström Per A R
Abstract excerpt
Retinitis pigmentosa is a blinding disease in which unknown mechanisms cause the degeneration of retinal photoreceptors. The retinal degeneration (rd1) mouse is a relevant model for this condition, since it carries a mutation also found in some forms of retinitis pigmentosa. To understand the degenerative process in the rd1 mouse, we must identify the survival and apoptosis-related signaling pathways in its...
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