Article

RIPK3 suppresses photoreceptor degeneration in a Stargardt disease mouse model

2026-04-29

Abstract excerpt

Autosomal recessive Stargardt disease type 1 (STGD1) is the most prevalent inherited juvenile macular degeneration, ultimately leading to irreversible blindness through photoreceptor cell loss, yet the underlying cell death mechanisms remain poorly defined. Receptor-interacting protein kinase 3 (RIPK3) is a well-established mediator of necroptosis and, under certain circumstances, apoptosis downstream of TNF famil...

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Literature Corpus work: ca9ac74b-b209-5ef1-b47d-8cb5f40ca6a6
DOI: 10.64898/2026.04.26.720951

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