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Article

Absence of p53 delays apoptotic photoreceptor cell death in the rds mouse.

Current eye research - 1 Sept 1998

Ali R R, Reichel M B, Kanuga N, Munro P M, Alexander R A, Clarke A R, Luthert P J, Bhattacharya S S, Hunt D M

Abstract excerpt

PURPOSE: This study was aimed at determining whether or not apoptotic photoreceptor cell death in a mouse model of inherited retinal degeneration is p53 dependent. METHODS: A colony of p53-deficient rds mice were obtained by crossing homozygous rds mice with animals homozygous for a targeted disr...

Topics

Animals
Apoptosis
DNA Primers
Gene Deletion
Genes, p53
Genotype
In Situ Nick-End Labeling
Mice
Mice, Inbred BALB C
Mice, Knockout
Photoreceptor Cells, Vertebrate
Retina

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Retinal Degeneration

Tumor Suppressor Protein p53

Source

Identifiers

PMID: 9746439
DOI: 10.1076/ceyr.17.9.917.5137

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9746439-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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