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Article

Redundant and Nonredundant Functions of Akt Isoforms in the Retina.

Advances in experimental medicine and biology - 1 Jan 2018

Rajala Raju V S, Rajala Ammaji

Abstract excerpt

Serine/threonine kinase Akt is a downstream effector of the phosphoinositide 3-kinase pathway that is involved in many processes, including providing neuroprotection to stressed photoreceptor cells. Akt exists in three isoforms designated as Akt1, Akt2, and Akt3. All of these isoforms are expressed in the retina. We previously reported that Akt2 knockout mice were susceptible to light stress-induced photoreceptor...

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Identifiers

PMID: 29721991
DOI: 10.1007/978-3-319-75402-4_71
PMCID: PMC6417426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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