Article
Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.
Scandinavian journal of immunology - 1 Mar 2005
Stefansson Thors V, Kolka R, Sigurdardottir S L, Edvardsson V O, Arason G, Haraldsson A
Abstract excerpt
Henoch-Schonlein purpura (HSP) is a vasculitis of unknown aetiology, possibly involving immune complexes. The complement system is essential for the clearance of immune complexes. Our aim was to explore the hypothesis that patients with HSP have abnormal complements, contributing to the development of the disease. The study included 56 patients diagnosed with HSP at the Children's Hospital, Iceland between 1984...
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