Article
C4AQ0 superimposed on a primary defect increases the susceptibility to systemic lupus erythematosus (SLE) in a family with association between C4AQ0 and SLE.
The Journal of rheumatology - 1 Nov 1998
Traustadóttir K H, Steinsson K, Erlendsson K
Abstract excerpt
OBJECTIVE: To investigate the association of C4AQ0 with increased incidence of systemic lupus erythematosus (SLE) or positive serology (28%) in an extended Icelandic family, and whether this can be explained by impaired complement function in handling immune complexes (IC). METHODS: The ability o...
Topics
- Antigen-Antibody Complex
- Complement C4a
- Erythrocytes
- Female
- Genetic Predisposition to Disease
- Heterozygote
- Homozygote
- Humans
- Lupus Erythematosus, Systemic
- Male
- Pedigree
- Reference Values
