Article
Variable number of tandem repeat of the 5'-flanking region of type-C human natriuretic peptide receptor gene influences blood pressure levels in obesity-associated hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Oct 2004
Aoi Noriko, Soma Masayoshi, Nakayama Tomohiro, Rahmutula Dolkun, Kosuge Kotoko, Izumi Yoichi, Matsumoto Koichi
Abstract excerpt
The gene for natriuretic peptides receptor C (NPRC), which is a candidate susceptibility gene for essential hypertension (EH) or obese hypertension, plays a key role in the regulation of plasma levels and biological effects of natriuretic peptides. The aims of the present study were to find new genetic markers in the 5'-flanking region of the NPRC gene and to assess relationships between variants and phenotypes...
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