Article
Characterization of novel 3'untranslated regions and related polymorphisms of the gene NPPC, encoding for the C-type natriuretic peptide.
Peptides - 1 Jun 2013
Melaiu O, Facioni M S, Cabiati M, Caruso R, Giannessi D, Landi S, Gemignani F, Del Ry S
Abstract excerpt
Elevated plasmatic levels of C-type natriuretic peptide (CNP) were found in patients with chronic heart failure (CHF), but its use as sensitive and specific clinical bio-marker is still controversial. In fact, high levels of CNP were also observed in patients classified in low severity New York Heart Association (NYHA) classes. CNP is encoded by a gene poorly studied (NPPC, natriuretic-precursor peptide C), where...
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