Article

An exhaustive analysis of single amino acid variants in helical transmembrane proteins

2019-12-19

Abstract excerpt

Single nucleotide variants (SNVs) have been widely studied in the past due to being the main source of human genetic variation. Less is known about the effect of single amino acid variants (SAVs) due to the immense resources required for comprehensive experimental studies. In contrast, in silico methods predicting the effects of sequence variants upon molecular function and upon the organism are readily available...

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Literature Corpus work: d26b7fe4-c6a8-5cc7-b70c-4cd84fb1beee
DOI: 10.1101/2019.12.18.881318

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