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Article

Structural location of disease-associated single-nucleotide polymorphisms.

Journal of molecular biology - 11 Apr 2003

Stitziel Nathan O, Tseng Yan Yuan, Pervouchine Dimitri, Goddeau David, Kasif Simon, Liang Jie

Abstract excerpt

Non-synonymous single-nucleotide polymorphism (nsSNP) of genes introduces amino acid changes to proteins, and plays an important role in providing genetic functional diversity. To understand the structural characteristics of disease-associated SNPs, we have mapped a set of nsSNPs derived from the online mendelian inheritance in man (OMIM) database to the structural surfaces of encoded proteins. These nsSNPs are...

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PMID: 12662927
DOI: 10.1016/s0022-2836(03)00240-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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