Article
Beta2 adrenergic receptor gene Arg16Gly polymorphism is associated with therapeutic efficacy of benazepril on essential hypertension in Chinese.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Aug 2004
Huang Guo, Xing Houxun, Hao Ke, Peng Shaojie, Wu Di, Guang Wenwei, Huang Aiqun, Hong Xiumei, Wang Yuanping, Feng Yan, Zhang Yan, Li Jianping, Chen Changzhong, Wang Binyan, Zhang Xuejun, Li Dong, Yu Yunxian, Liu Jing, Zhu Guoying, Huo Yong, Chen Dafang, Hou Yongtai, Wang Xiaobin, Xu Xin, Niu Tianhua, Xu Xiping
Abstract excerpt
BACKGROUND: There is considerable variability in individual response to antihypertensive agents. The reason for this is not known, but may be related to individual genetic variability. This study examined whether the therapeutic efficacy of benazepril on essential hypertension is modified by beta2 adrenergic receptor gene (ADRB2) Arg16Gly (R16G) polymorphism. METHODS AND RESULTS: We conducted a family-based study...
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