Article
Modeling the genetic etiology of pharmacokinetic-pharmacodynamic links with the ARMA process.
Journal of biopharmaceutical statistics - 1 Mar 2010
Lin Min, Berg Arthur, Wu Rongling
Abstract excerpt
Substantial variability exists among different patients in response to drugs. The identification of genetic factors that contribute to the interpersonal differentiation has been an important task for pharmacogenetic research and drug discovery. In this article, we have derived a high-dimensional statistical model for unveiling the genetic machinery for drug response by integrating two different but biologically...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
