Article
Sequencing complex diseases With HapMap.
Genetics - 1 Sept 2004
Liu Tian, Johnson Julie A, Casella George, Wu Rongling
Abstract excerpt
Determining the patterns of DNA sequence variation in the human genome is a useful first step toward identifying the genetic basis of a common disease. A haplotype map (HapMap), aimed at describing these variation patterns across the entire genome, has been recently developed by the International HapMap Consortium. In this article, we present a novel statistical model for directly characterizing specific sequence...
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