Article
Residues Met76 and Gln79 in HLA-G alpha1 domain involve in KIR2DL4 recognition.
Cell research - 1 Mar 2005
Yan Wei Hua, Fan Li An
Abstract excerpt
Human leukocyte antigen-G (HLA-G) has long been speculated as a beneficial factor for a successful pregnancy for its restricted expression on fetal-maternal extravillous cytotrophoblasts and its capability of modulating uterine natural killer cell (uNK) function such as cytotoxicity and cytokine production through NK cell receptors. HLA class I alpha1 domain is an important killer cell Ig-like receptor (KIR)...
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