Article
Prevalence and clinical implications of HFE gene mutations (C282Y and H63D) in patients with chronic hepatitis B and C in Taiwan.
Liver international : official journal of the International Association for the Study of the Liver - 1 Apr 2005
Mah Yone-Han, Kao Jia-Horng, Liu Chun-Jen, Chen Chi-Ling, Chen Pei-Jer, Lai Ming-Yang, Chen Ding-Shinn
Abstract excerpt
BACKGROUND/AIMS: The implication of hemochromatosis (HFE) gene mutations in chronic viral hepatitis remains controversial. We therefore studied the prevalence of HFE mutations and their impact on the progression of chronic viral hepatitis in Taiwan. PATIENTS & METHODS: H63D and C282Y mutations were screened by using polymerase chain reaction followed by restriction fragment length polymorphism in 152 chronic...
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