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Article

Iron overload and HFE gene mutations in Czech patients with chronic liver diseases.

Disease markers - 1 Jan 2012

Dostalikova-Cimburova Marketa, Kratka Karolina, Stransky Jaroslav, Putova Ivana, Cieslarova Blanka, Horak Jiri

Abstract excerpt

The aim of the study was to identify the prevalence of HFE gene mutations in Czech patients with chronic liver diseases and the influence of the mutations on iron status. The presence of HFE gene mutations (C282Y, H63D, and S65C) analyzed by the PCR-RFLP method, presence of cirrhosis, and serum iron indices were compared among 454 patients with different chronic liver diseases (51 with chronic hepatitis B, 122...

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Source

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Identifiers

PMID: 22297603
DOI: 10.3233/DMA-2012-0861
PMCID: PMC3826488

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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