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Association of HFE gene C282Y and H63D mutations with liver cirrhosis in the Lithuanian population.

Medicina (Kaunas, Lithuania) - 1 Jan 2016

Juzėnas Simonas, Kupčinskas Juozas, Valantienė Irena, Šumskienė Jolanta, Petrenkienė Vitalija, Kondrackienė Jūrate, Kučinskas Laimutis, Kiudelis Gediminas, Skiecevičienė Jurgita, Kupčinskas Limas

Abstract excerpt

BACKGROUND AND OBJECTIVE: Liver cirrhosis is the end-stage disease of chronic liver injury. Due to differences in the natural course of chronic liver diseases, identification of genetic factors that influence individual outcomes is warranted. HFE-linked hereditary hemochromatosis (HH) predisposes disease progression to cirrhosis; however, the role of heterozygous C282Y or H63D mutations in the development of...

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PMID: 27816425
DOI: 10.1016/j.medici.2016.09.004

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HFE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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