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Article

Possible risk modification by polymorphisms of estrogen metabolizing genes in familial breast cancer susceptibility in an Indian population.

Cancer investigation - 1 Mar 2010

Syamala Volga S, Syamala Vani, Sheeja V R, Kuttan Ratheesan, Balakrishnan Rajan, Ankathil Ravindran

Abstract excerpt

This case control study investigated whether polymorphisms of estrogen metabolizing genes CYP1A1 MspI, CYP17 MspAI, COMT Val(158) Met, and SULT1A1 Arg(213) His have any role in familial breast cancer susceptibility risk. Logistic regression analysis adjusted to age was used to calculate odds ratios (ORs) and 95% confidence intervals (95%CIs). Familial breast cancer risk due to CYP1A1 wt/m1 and m1/m1 genotypes was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Catechol O-Methyltransferase

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Share to Polymorphism, Genetic

Share to Steroid 17-alpha-Hydroxylase

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Identifiers

PMID: 19863350
DOI: 10.3109/07357900902744494

Genes

COMT

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