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Article

Cytochrome P450 CYP1B1 and catechol O-methyltransferase (COMT) genetic polymorphisms and breast cancer susceptibility in a Turkish population.

Archives of toxicology - 1 Nov 2002

Kocabaş Neslihan Aygün, Sardaş Semra, Cholerton Suzanne, Daly Ann K, Karakaya Ali Esat

Abstract excerpt

Epidemiological studies indicate that most risk factors for breast cancer are related to reproductive and hormonal factors. Estrogen has been proposed to trigger breast cancer development via an initiating mechanism involving its metabolite, catechol estrogen (CE). Because of the important role o...

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Source

Identifiers

PMID: 12415427
DOI: 10.1007/s00204-002-0387-x

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12415427-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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