Article
Polymorphisms of catechol estrogens metabolism pathway genes and breast cancer risk in Mexican women.
Breast (Edinburgh, Scotland) - 1 Jun 2013
Martínez-Ramírez O C, Pérez-Morales R, Castro C, Flores-Díaz A, Soto-Cruz K E, Astorga-Ramos A, Gonsebatt M E, Casas L, Valdés-Flores M, Rubio J
Abstract excerpt
Breast cancer is associated to estrogen exposure. Allelic variants involved in estrogen metabolism might change the risk of developing this neoplasia. We examined the potential association of breast cancer risk in Mexican women with the polymorphisms CYP1A1 rs1048943, CYP1B1 rs1056836, COMT rs4680, GSTP1 rs1695, GSTT1 null and GSTM1 null which are involved in estrogen metabolism pathway. This study included 150...
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