Article
Sp-family of transcription factors regulates human SHIP2 gene expression.
Gene - 28 Mar 2005
Ishida Satoru, Funakoshi Akihiro, Miyasaka Kyoko, Iguchi Haruo, Takiguchi Soichi
Abstract excerpt
We have characterized the regulation of human SH-2 containing inositol 5'-phosphatase 2 (SHIP2) gene expression. First, the transcription initiation sites and the sequence of the 5' upstream region of human SHIP2 gene were elucidated. Next, the minimal promoter of the human SHIP2 gene was identified by reporter gene assays in HL60 cells and differentiated human subcutaneous white adipocytes. An Sp1 element...
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