Article
An autosomal genomic scan for loci linked to type 2 diabetes in northern Han Chinese.
Journal of molecular medicine (Berlin, Germany) - 1 Mar 2005
Zhao J Y, Xiong M M, Huang W, Wang H, Zuo J, Wu G D, Chen Z, Qiang B Q, Zhang M L, Chen J L, Ding W, Yuan W T, Xu H Y, Jin L, Li Y X, Sun Q, Liu Q Y, Boerwinkle E, Fang F D
Abstract excerpt
We report the results of a genome-wide scan conducted in 219 individuals from 34 large multiplex nuclear pedigrees from the northern Han Chinese population at an average resolution of about 10 cM. Nonparametric two-point and multipoint linkage analyses were performed to detect evidence of linkage with type 2 diabetes in this study. On chromosome 1 four regions showed evidence of linkage with type 2 diabetes in...
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