Article
Genome-wide scan for type 2 diabetes loci in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25.
Diabetes - 1 Jun 2004
Ng Maggie C Y, So Wing-Yee, Cox Nancy J, Lam Vincent K L, Cockram Clive S, Critchley Julian A J H, Bell Graeme I, Chan Juliana C N
Abstract excerpt
We conducted an autosomal genome scan to map loci for type 2 diabetes in a Hong Kong Chinese population. We studied 64 families, segregating type 2 diabetes, of which 57 had at least one member with an age at diagnosis of </=40 years. These families included a total of 126 affected sibpairs and 4 other affected relative pairs. Nonparametric linkage analysis revealed seven regions showing nominal evidence for...
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