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Article

Role of Transforming Growth Factor Beta in Human Cancer

18 Mar 2005

Abstract excerpt

Transforming growth factor beta (TGF-beta) is a ubiquitous and essential regulator of cellular and physiologic processes including proliferation, differentiation, migration, cell survival, angiogenesis, and immunosurveillance. Alterations in the TGF-beta signaling pathway, including mutation or deletion of members of the signaling pathway and resistance to TGF-beta-mediated inhibition of proliferation are...

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Identifiers

PMID: 15774796
DOI: 10.1200/jco.2005.02.047

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Source receipt: pubmed, retrieved 7 Sept 2026.

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