Article
Transforming growth factor-beta signaling in cancer.
Microscopy research and technique - 15 Feb 2001
Rich J, Borton A, Wang X
Abstract excerpt
Transforming growth factor (TGF-beta) is a multifunctional polypeptide implicated in the regulation of a variety of cellular processes including growth, differentiation, apoptosis, adhesion, and motility. Abnormal activation or inhibition of these TGF-beta regulated processes is implicated in many diseases, including cancer. Cancers can develop through selective exploitation of defects in TGF-beta signaling that...
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