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Exploring TGF-β Signaling in Cancer Progression: Prospects and Therapeutic Strategies

1 Feb 2025

Abstract excerpt

Cancer persists as a ubiquitous global challenge despite the remarkable advances. It is caused by uncontrolled cell growth and metastasis. The Transforming Growth Factor-beta (TGF-β) signaling pathway is considered a primary regulator of various normal physiological processes in the human body. Recently, factors determining the nature of TGF-β response have received attention, specifically its signaling pathway...

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PMID: 39989503
DOI: 10.2147/ott.s493643

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