Article
Conformationally sensitive residues in extracellular loop 5 of the Na+/dicarboxylate co-transporter.
The Journal of biological chemistry - 13 May 2005
Pajor Ana M, Randolph Kathleen M
Abstract excerpt
The Na+/dicarboxylate co-transporter, NaDC-1, from the kidney and small intestine, transports three sodium ions together with one divalent anion substrate, such as succinate2-. A previous study (Pajor, A. M. (2001) J. Biol. Chem. 276, 29961-29968), identified four amino acids, Ser-478, Ala-480, Ala-481, and Thr-482, near the extracellular end of transmembrane helix (TM) 9 that are likely to form part of the...
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