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Article

The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans.

The journal of pain - 1 Mar 2005

Fillingim Roger B, Kaplan Lee, Staud Roland, Ness Timothy J, Glover Toni L, Campbell Claudia M, Mogil Jeffrey S, Wallace Margaret R

Abstract excerpt

Responses to painful stimuli are characterized by tremendous interindividual variability, and genetic factors likely account for some proportion of this variability. However, few studies have identified genetic contributions to experimental pain perception in humans. This experiment investigated whether the A118G single nucleotide polymorphism of the mu-opioid receptor gene ( OPRM1 ) was associated with responses...

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Source

Identifiers

PMID: 15772909
DOI: 10.1016/j.jpain.2004.11.008

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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