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Article

Assessment of opioid receptor μ1 gene A118G polymorphism and its association with pain intensity in patients with fibromyalgia.

Rheumatology international - 1 Sept 2014

Solak Özlem, Erdoğan Müjgan Özdemir, Yıldız Handan, Ulaşlı Alper Murat, Yaman Fatima, Terzi Evrim Suna Arıkan, Ulu Sena, Dündar Ümit, Solak Mustafa

Abstract excerpt

Fibromyalgia may present with widespread pain and tenderness, fatigue, anxiety, and depression and is associated with a low pain threshold. The etiology of fibromyalgia is yet to be ascertained, although both genetic and environmental factors may play a role in the susceptibility of patients to fibromyalgia. Various genetic variations have been investigated to explain fibromyalgia susceptibility and differences...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24671502
DOI: 10.1007/s00296-014-2995-1

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Assessment of opioid receptor μ1 gene A118G polymorphism and its association with pain intensity in patients with fibromyalgia.PMID 24671502Read ↗

Identification of candidate genes associated with fibromyalgia susceptibility in southern Spanish women: the al-Ándalus project.Semantic proximity Read ↗

The human μ-opioid receptor gene polymorphism (A118G) is associated with head pain severity in a clinical cohort of female migraine with aura patients.Semantic proximity Read ↗

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Fibromyalgia: A Review of Related Polymorphisms and Clinical RelevanceSemantic proximity Read ↗

Candidate gene studies of fibromyalgia: a systematic review and meta-analysis.Semantic proximity Read ↗

Does human serotonin-1A receptor polymorphism (rs6295) code for pain and associated symptoms in fibromyalgia syndrome?Semantic proximity Read ↗

Catechol-O-methyltransferase Val158Met polymorphism influences anxiety, depression, and disability, but not pressure pain sensitivity, in women with fibromyalgia syndrome.Semantic proximity Read ↗

Effects of OPRM1 A118G polymorphism on epidural analgesia with fentanyl during labor: a meta-analysis.Semantic proximity Read ↗

Gene-to-gene interactions regulate endogenous pain modulation in fibromyalgia patients and healthy controls-antagonistic effects between opioid and serotonin-related genes.Semantic proximity Read ↗

Allele frequency and genotype distribution of the opioid receptor μ-1 (OPRM1) A118G polymorphism in the Western Saudi population.Semantic proximity Read ↗

The μ-opioid receptor gene polymorphism 118A>G weakens the pharmacological action of buprenorphine.Semantic proximity Read ↗

Consequences of the 118A&gt;G polymorphism in the OPRM1 gene: translation from bench to bedside?Semantic proximity Read ↗

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