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Article

Ethnicity interacts with the OPRM1 gene in experimental pain sensitivity.

Pain - 1 Aug 2012

Hastie Barbara A, Riley Joseph L, Kaplan Lee, Herrera Dyanne G, Campbell Claudia M, Virtusio Kathrina, Mogil Jeffrey S, Wallace Margaret R, Fillingim Roger B

Abstract excerpt

Robust interindividual variation in pain sensitivity has been observed, and recent evidence suggests that some of the variability may be genetically mediated. Our previous data revealed significantly higher pressure pain thresholds among individuals possessing the minor G allele of the A118G SNP of the mu-opioid receptor gene (OPRM1) compared with those with 2 consensus alleles. Moreover, ethnic differences in...

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Source

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Identifiers

PMID: 22717102
DOI: 10.1016/j.pain.2012.03.022
PMCID: PMC3683662

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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