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Article

The genetic influences on oxycodone response characteristics in human experimental pain.

Fundamental & clinical pharmacology - 1 Aug 2015

Olesen Anne E, Sato Hiroe, Nielsen Lecia M, Staahl Camilla, Droney Joanne, Gretton Sophy, Branford Ruth, Drewes Asbjørn M, Arendt-Nielsen Lars, Riley Julia, Ross Joy

Abstract excerpt

Human experimental pain studies are of value to study basic pain mechanisms under controlled conditions. The aim of this study was to investigate whether genetic variation across selected mu-, kappa- and delta-opioid receptor genes (OPRM1, OPRK1and OPRD1, respectively) influenced analgesic response to oxycodone in healthy volunteers. Experimental multimodal, multitissue pain data from previously published studies...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26042474
DOI: 10.1111/fcp.12128

Genes

OPRM1
OPRD1
OPRK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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