Article

The adhesion GPCR VLGR1/ADGRV1 regulates focal adhesion turnover by controlling their assembly

2023-01-04

Abstract excerpt

VLGR1/ADGRV1 (very large G protein-coupled receptor-1) is the largest adhesion G protein-coupled receptor aGPCRs. Mutations in VLGR1/ADGRV1 are associated with human Usher syndrome (USH), the most common form of deaf-blindness, and also with epilepsy in humans and in mice. Although VLGR1 is almost ubiquitously expressed in CNS and ocular and inner ear sensory cells. Little is known about the pathogenesis of the di...

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Literature Corpus work: 97c32711-5cc2-567d-98be-35b46a64187f
DOI: 10.22541/au.167285899.92478599/v1

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