Article
Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation.
Molecular psychiatry - 1 Jul 2005
Szeszko P R, Lipsky R, Mentschel C, Robinson D, Gunduz-Bruce H, Sevy S, Ashtari M, Napolitano B, Bilder R M, Kane J M, Goldman D, Malhotra A K
Abstract excerpt
Magnetic resonance (MR) imaging studies have identified hippocampal structural alterations in the pathogenesis of schizophrenia. Brain-derived neurotrophic factor (BDNF) is one of the neurotrophins that is widely expressed in the hippocampal formation and has been implicated in the neurobiology of schizophrenia. Polymorphisms in the BDNF gene may therefore confer risk for schizophrenia through hippocampal...
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