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Article

Influence of BDNF and MTHFR polymorphisms on hippocampal volume in first-episode psychosis.

Schizophrenia research - 1 Sept 2020

Pujol Nuria, Mané Anna, Bergé Daniel, Mezquida Gisela, Amoretti Silvia, Pérez Lucía, González-Pinto Ana, Barcones Fe, Cuesta Manuel J, Sánchez-Tomico Georgina, Vieta Eduard, Castro-Fornieles Josefina, Bernardo Miquel, Parellada Mara

Abstract excerpt

BACKGROUND: The BDNF and MTHFR genes are independently linked to the pathogenesis of schizophrenia and its neuroimaging correlates. The aim of this study was to explore, for the first time, the individual and interactional effects of the Val66Met and C677T polymorphisms on hippocampal atrophy in first-episode psychosis (FEP). METHOD: Multi-site case-control study based on clinical, genetic (rs 6265, rs 1801133)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32988741
DOI: 10.1016/j.schres.2020.08.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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