Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HBx expression activates RhoA GTPase: impact on cell migration.

Cell biology international - 1 Feb 2011

Feng Huixing, Li Xi, Niu Dandan, Ning Chen Wei

Abstract excerpt

HBV (hepatitis B virus) remains a global health concern, especially in developing countries. It has been associated with the development of HCC (hepatocellular carcinoma). One of the four viral proteins, HBx, interacts with cellular proteins, which are involved in a series of cellular processes including cell migration. The Rho GTPases (guanine nucleotide triphosphatases) family of proteins is involved in the...

Topics

Actins
Cell Movement
Genotype
Hep G2 Cells
Hepatitis B virus
Humans
Trans-Activators
Transfection
Viral Regulatory and Accessory Proteins
rhoA GTP-Binding Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20977432
DOI: 10.1042/CBI20100101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

HBx expression activates RhoA GTPase: impact on cell migration.PMID 20977432Read ↗

The hepatitis B virus X protein (HBx) induces a migratory phenotype in a CD44-dependent manner: possible role of HBx in invasion and metastasis.Semantic proximity Read ↗

Hepatitis B virus X protein promotes cell migration by inducing matrix metalloproteinase-3.Semantic proximity Read ↗

[Experimental study of epithelial-mesenchymal transition induced by HBx protein in liver cancer cell].Semantic proximity Read ↗

Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication.Semantic proximity Read ↗

EphrinB1 promotes cancer cell migration and invasion through the interaction with RhoGDI1Semantic proximity Read ↗

Diverse roles of guanine nucleotide exchange factors in regulating collective cell migration.Semantic proximity Read ↗

Spatiotemporal Analysis of Hepatitis B Virus X Protein in Primary Human HepatocytesSemantic proximity Read ↗

Adhesion contact kinetics of HepG2 cells during Hepatitis B virus replication: Involvement of SH3-binding motif in HBX.Semantic proximity Read ↗

Hepatitis B virus X protein upregulates HSP90alpha expression via activation of c-Myc in human hepatocarcinoma cell line, HepG2Semantic proximity Read ↗

Hepatitis B Virus X Protein Induces Perinuclear Mitochondrial Clustering in Microtubule- and Dynein-Dependent MannersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.