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Article

Phenotypic characterization of isolated valvular interstitial cell subpopulations.

The Journal of heart valve disease - 1 Nov 2006

Blevins Tracy L, Carroll Joshua L, Raza Alina M, Grande-Allen K Jane

Abstract excerpt

BACKGROUND AND AIM OF THE STUDY: Valvular interstitial cells (VICs) demonstrate a heterogeneous range of phenotypes such as variable expression of smooth muscle alpha-actin (SMalphaA). Myofibroblast-like VICs, expressing high levels of SMalphaA, are thought to be involved in myxomatous degeneration of mitral valves. The inability to isolate specific cell types has restricted potential investigations of valvular...

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PMID: 17152790

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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