Article
Heterogeneity of bladder myocytes in vitro: modulation of myosin isoform expression.
Tissue & cell - 1 Jun 2001
Arafat H A, Kim G S, DiSanto M E, Wein A J, Chacko S
Abstract excerpt
We studied the expression of myosin heavy chain isoforms differing at the N-terminal (SM-A, SM-B) and the C-terminal (SM1, SM2) regions and non-muscle myosin heavy chain II-A and II-B (NMMHC II-A and B) in newborn and adult rabbit bladder smooth muscle cells (SMCs) and in cultures of enzymatically dissociated neonatal detrusor. RT-PCR analyses revealed that 94.5+/-3.27% of MHC transcripts of the adult bladder...
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