Article
[Expression and mutation of Fas-associated death domain (FADD) gene in non-small cell lung cancer].
Ai zheng = Aizheng = Chinese journal of cancer - 1 Mar 2005
Yang Qin, Zhu Run-Qing, Fang Zhong, Xia Dong, Diao Lu-Ming, Liu Ming-Qiu
Abstract excerpt
BACKGROUND & OBJECTIVE: Abnormal expression of Fas-associated death domain (FADD) protein, an important adapter in cell apoptosis signal conduction, may closely relate with tumorigenesis. This study was to detect expression and mutation of FADD gene in non-small cell lung cancer (NSCLC), evaluate its effect on development of NSCLC, and explore the mechanism. METHODS: Polymerase chain reaction and single-strand...
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