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Article

Association of polymorphisms in the cyclin D1 and XPD genes and susceptibility to cancers of the upper aero-digestive tract.

Molecular carcinogenesis - 1 Apr 2005

Buch Shama, Zhu Bing, Davis Autumn Gaither, Odom Dominic, Siegfried Jill M, Grandis Jennifer R, Romkes Marjorie

Abstract excerpt

DNA repair enzyme genetic polymorphisms have been postulated to increase the risk of certain cancers in the presence of tobacco carcinogen exposures. The XPD protein is an important component of the TFIIH transcription factor complex. XPD genetic polymorphisms resulting in amino acids substitutions may lead to alterations in TFIIH helicase activity, resulting in repair and transcription defects. Cyclin D1 is a...

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Identifiers

PMID: 15754315
DOI: 10.1002/mc.20086

Genes

CCND1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of polymorphisms in the cyclin D1 and XPD genes and susceptibility to cancers of the upper aero-digestive tract.PMID 15754315Read ↗

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Cyclin D1 polymorphism and risk for squamous cell carcinoma of the head and neck: a case-control studySemantic proximity Read ↗

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Association of cyclin D1 genotypes with nasopharyngeal carcinoma risk.Semantic proximity Read ↗

XPD/ERCC2 polymorphisms and risk of head and neck cancer: a case-control analysis.Semantic proximity Read ↗

DNA repair gene XPD polymorphisms and cancer risk: a meta-analysis based on 56 case-control studies.Semantic proximity Read ↗

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